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Alzheimer's and Dementia

What is it - how to treat it.


The brain is, by a wide margin, the most amazing part of the human body. It controls the conditions of growth, temperature, coordination, balance, sleep, learning, taste, speech, morality, problem solving skills, visual coordination, aggression, creativity, meditation and sexuality.

The brain consists of billions of nerve cells (neurons) which control specific functions such as emotion, memory and judgment.  Specific parts of the brain transmit information throughout the body for it to perform its daily functions. The brain is contantly generating an endless number of synapses (connection points). Through the synapses, we are able to move, feel emotions, and do many other things. By synapses the brain communicates with the rest of the body and without them we would not be able to perform many actions. 

When the brain is affected, such as diseases or accidents, is when synaptic connections are interrupted and the entire body is affected.

What are the symptoms and how do they evolve?

In neurodegenerative diseases such as Alzheimer's disease, neurons are sick and communication between them is interrupted. Although the cause of Alzheimer's disease is not known exactly, the disease causes in each patient, the decline of intellectual functions in comparison with the level of function before. This decline affects many aspects of life, including personal, profesional and social activities.  

Alzheimer's disease affects all social groups and makes no distinction between gender, ethnicity or geographical location. It usually affects people aged 60 and older, although it can also occur in younger patients.

The most common symptoms are related to memory loss, difficulties with language, reasoning, thinking, disorientation in time and space, trouble performing familiar and usual activities, changes in behavior, mood and personality. Deterioration is gradual and progressive.

How is the diagnosis established?

It is extremely important to make an early diagnosis. There are many symptoms that can be confused with mental illness and can be misdiagnosed. It is essential to have a thorough examination, together with laboratory studies, complete physical and neurological examination, neuropsychological testing, EEG, imaging (CT scans, magnetic resonance imaging, SPECT, Brain Mapping, etc..).

Unfortunately, Alzheimer's disease is only confirmed with a pathology study once the person has died. However, current methods can reach a level of certainty, almost exactly, as to what is happening to the patient’s brain.

For a diagnosis, one should consult a neurologist.

For proper treatment, one should consult a neurologist.

What is the treatment of dementia?

There is currently no cure for Alzheimer's disease. Most treatments do not reverse or halt the progression of the disease; Some improve symptoms and slow progression but fail to restore the existing brain damage, or stop the progression to advanced stages of the disease.

Among the areas of interest is the search for modifying treatments of Alzheimer's disease and the use of Neurotrophic Factors.

Neurotrophic Factors are small proteins that promote the vitality and maintenance of neurons. They are responsible for maintaining the function, growth, development, recovery and survival of neurons.

New findings demonstrate that neurons can recover and regenerate in neurodegenerative diseases.

Cerebrolysin is a drug that stimulates the vitality of neurons, promoting regeneration and improving connectivity. Cerebrolysin is a preparation of active peptides acting as Endogenous Neurotrophic Factors.

Cerebrolysin has worldwide clinical experience and ongoing clinical research.

This information is provided as an educational service of EVER NEURO PHARMA

Did you know ...?

There are an estimated 35.6 million people worldwide with dementia, mainly Alzheimer type and this figure is estimated to nearly double every 20 years. An estimated 2030 averaged 65.7 million patients and 2050 approximately 115.4 million will suffer it. Disease is forecast growing. Dementia and Alzheimer originate challenge to science and society, for its huge negative impact to the social and economic fields.

What are the early symptoms of Alzheimer's disease?

The symptoms of Alzheimer's disease (AD) in the initial stage may be simple and / or undetectable, but are recurrent and increasing. As the disease progresses, memory loss occurs, and appears the difficulty to be oriented in time, place and situation. This manifestation is called "loss of short term memory," which generates patient confusion, insecurity and anxiety, having difficulty interacting in all areas, family, social, economic and areas inhabited.

Alzheimer's disease does not affect all memory types with the same intensity and speed, for example: "The long-term memory" are the old memories and tasks learned by the body and perform actions such as hold and use a spoon etc.. This memory is affected to a lesser degree.

Besides the ability to learn new things and create new memories is affected.

How is a diagnosis of Alzheimer's disease established?

The diagnosis was based first on patient history, clinical observation of specialist and referrals from family.

Is based on the neurological and psychological deficits, and difficulties in different conditions.

It is necessary to evaluate the patient before treatment with neuropsychological tests, neurophysiologic studies for electrical brain functioning as well as neuroimaging that will both support for the expected deterioration pictures and discard other diseases.

Lately it has also shown differences in the normal biochemical pattern, so a spectroscopic study is also very useful.

Finally, positron emission tomography (PET) reveals the specific changes at the neuronal level in Alzheimer's disease, although the cost of this study is high.

Who can indicate cerebrolysin?

The specialist indicated cerebrolysin in neurodegenerative disorders such as Alzheimer's disease, as well as to minimize damage and sequelae in cerebro-vascular disease (CVD) (Strokes).

What improvement can be expected with cerebrolysin treatment?

Clinical studies with cerebrolysin have shown beneficial effects on clinical outcomes in global memory and cognition; also minimizes or slows neurodegeneration and helps form new nerve connections (synapses). These results are more evident in the second treatment cycle.

How to use cerebrolysin?

It is a personalized treatment and only medical specialist establishes its use, dosage and duration.

It's important to punctually follow all directions and recommendations.

Attachment to any therapy is essential to achieve the desired therapeutic goals.

Cerebrolysin is preferably administered intravenously, only under medical supervision.

What to do when left to manage one day cerebrolysin?

Resume the next day cerebrolysin therapy and meet the dose and duration of treatment prescribed by the medical specialist to ensure beneficial results.

What are the most common adverse effects with the use of cerebrolysin?

Cerebrolysin proved to be well tolerated in clinical studies, being mild most of the adverse effects. You can generally occur dizziness or vertigo, headache, nausea and increased sweating.